ASS1P14

Across TCGA pan-cancer cohorts, ASS1P14 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of ASS1P14’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where ASS1P14 RNA is repressed in tumor relative to normal tissue. In most cancer types ASS1P14 is over-expressed in tumor, although a few such as KIRP and KIRC show the opposite, repressed pattern.

KIRP, KIRC, and KICH are the cancer types where ASS1P14 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ASS1P14 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	All	III,IV	−0.368	<.001	10	view →
KIRC	Male	All	−0.156	<.001	9	view →
KICH	Female	All	−0.159	.001	4	view →
STAD	All	II,III,IV	+0.118	.020	2	view →
LUAD	All	All	+0.050	.004	2	view →
LUSC	All	All	+0.046	.003	2	view →
PRAD	All	All	−0.030	.010	2	view →
COAD	Female	II,III,IV	+0.367	.020	1	view →
LIHC	Female	All	−0.113	.047	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

ASS1P14–KIRP

Open the KIRP breakdown →