ASS1P12

Across TCGA pan-cancer cohorts, ASS1P12 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated ASS1P12 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher ASS1P12 RNA is associated with better overall survival. In most high-consensus cancer types, elevated ASS1P12 expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCS show a favorable association.

HNSC, KIRP, and MESO are the cancer types where ASS1P12 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	All	0.757	0.609	<.001	76	view →
KIRP	DFS	Median	All	0.794	0.927	.001	60	view →
MESO	OS	Tertile	All	0.295	0.542	.001	54	view →
ACC	DFS	Quartile	All	0.370	0.721	.006	37	view →
UCS	DFS	Median	IV	0.952	0.367	.001	36	view →
ESCA	DFS	Quartile	All	0.293	1.000	.009	21	view →
GBM	DFS	Tertile	All	0.454	0.204	.004	18	view →
LGG	DFS	Tertile	All	0.768	0.876	.003	18	view →
SKCM	OS	Quartile	III,IV	0.612	0.272	.001	14	view →
KIRC	DFS	Tertile	III,IV	0.583	0.359	.026	14	view →
THCA	DFS	Quartile	IV	0.386	0.867	.004	14	view →
BRCA	DFS	Quartile	II,III,IV	0.474	0.649	.008	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

ASS1P12–HNSC (OS)

Open the HNSC breakdown →