Across TCGA pan-cancer cohorts, ASS1P11 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated ASS1P11 data layer.
The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher ASS1P11 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated ASS1P11 expression acts as an unfavorable survival marker, although some lineages such as KIRP and THCA show a favorable association.
KIRP, THCA, and CESC are the cancer types where ASS1P11 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.