ASS1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ASS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,934 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible ASS1-associated GO terms across cancer lineages are Response to mycotoxin, Cellular response to ammonium ion, and Cellular response to oleic acid. Each is linked with ASS1 in more than 19 cancer types. Because this analysis shows association rather than direction, both ASS1-to-partner and partner-to-ASS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to mycotoxin grouped by ASS1-low versus ASS1-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ASS1→partner) and Y-score (partner→ASS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUSCResponse to mycotoxin →+1.485+4.302<.001<.001320
BLOOD_LeukemiaCellular response to ammonium ion →+1.482+5.222<.001<.001320
KIDNEYCellular response to oleic acid →+1.206+2.111<.001<.001320
BLOOD_MyelomaMidgut development →+1.381+4.469<.001<.001318
KIDNEYResponse to oleic acid →+0.750+2.484.003<.001318
BONEL-arginine biosynthetic process →+0.646+2.574<.001<.001317
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,934 associations by consensus.

Response to mycotoxin by ASS1 expression — LUNG_NSCLC_LUSC

Box plot of Response to mycotoxin in ASS1-low vs ASS1-high samples in LUNG_NSCLC_LUSC.

Explore this box plot interactively →

Exploration