ASRGL1

Across TCGA patient cohorts, ASRGL1 mutation is significantly associated with the RNA expression of many other genes, with 121 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ASRGL1-associated genes across cancer lineages are RNU6-939P, MIR1207, and RNU1-64P. Each is linked with ASRGL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ASRGL1-to-partner and partner-to-ASRGL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-939P grouped by ASRGL1-low versus ASRGL1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ASRGL1→partner) and Y-score (partner→ASRGL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-939P →	+0.207	+4.245	<.001	.006	3	2
SKCM	MIR1207 →	+0.303	+3.669	<.001	.006	3	2
HNSC	RNU1-64P →	+0.823	+7.954	<.001	.008	3	1
UCEC	AQP7P4 →	+0.074	+3.805	<.001	.002	3	1
BLCA	ENO1P2 →	+0.043	+4.162	.005	.003	3	1
SKCM	SEPTIN7P12 →	+0.124	+3.906	.002	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 121 associations by consensus.

RNU6-939P by ASRGL1 expression — UCEC

Explore this box plot interactively →