ASPSCR1

Across TCGA pan-cancer cohorts, ASPSCR1 Mutation is linked to patient survival in 8 of 34 cancer types, making it a survival-associated ASPSCR1 data layer compared with 18 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher ASPSCR1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ASPSCR1 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

UCS, LIHC, and UCEC are the cancer types where ASPSCR1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	OS	Median	All	0.001	0.690	<.001	36	view →
LIHC	OS	Median	All	0.028	0.775	<.001	21	view →
UCEC	DFS	Median	All	1.000	0.830	.024	14	view →
SCLC	OS	Median	All	0.055	0.708	<.001	12	view →
HNSC	OS	Median	II,III,IV	0.069	0.757	<.001	12	view →
OV	OS	Median	II,III,IV	0.324	0.691	.049	6	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →
LUAD	DFS	Median	II,III,IV	0.098	0.682	<.001	6	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

ASPSCR1–UCS (OS)

Open the UCS breakdown →