ASPSCR1

Across TCGA pan-cancer cohorts, ASPSCR1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated ASPSCR1 data layer compared with 18 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher ASPSCR1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated ASPSCR1 expression acts as an unfavorable survival marker, although some lineages such as PDAC and LUAD show a favorable association.

GBM, LSCC, and PDAC are the cancer types where ASPSCR1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
GBM	DFS	Median	All	0.289	0.451	.009	11	view →
LSCC	DFS	Quartile	All	0.274	0.852	.012	6	view →
PDAC	OS	Tertile	IV	0.934	0.231	.024	4	view →
HNSC	OS	Quartile	II,III,IV	0.754	0.922	.021	2	view →
LUAD	OS	Median	II,III,IV	0.809	0.454	.039	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

ASPSCR1–GBM (DFS)

Open the GBM breakdown →