ASPSCR1

Across TCGA patient cohorts, ASPSCR1 protein abundance is significantly associated with the RNA expression of many other genes, with 15,862 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ASPSCR1-associated genes across cancer lineages are FOXK2, DCXR, and MFSD11. Each is linked with ASPSCR1 in more than 5 cancer types. Because this analysis shows association rather than direction, both ASPSCR1-to-partner and partner-to-ASPSCR1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ASPSCR1 versus FOXK2 in LSCC, with a Pearson correlation of 0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ASPSCR1→partner) and Y-score (partner→ASPSCR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	FOXK2 →	+0.579	+0.241	<.001	<.001	3	6
UCEC	DCXR →	+0.912	+0.209	<.001	.004	3	6
HNSC	MFSD11 →	+0.463	+0.258	<.001	<.001	3	6
BRCA	MED13 →	+0.653	+0.267	<.001	<.001	3	5
HNSC	NRL →	+0.431	+0.162	<.001	<.001	3	5
OV	UNK →	+0.597	+0.246	.004	.001	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,862 associations by consensus.

ASPSCR1 vs FOXK2 — LSCC

Explore this scatter interactively →