ASPSCR1

Across TCGA cell cohorts, ASPSCR1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,195 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ASPSCR1-associated GO terms across cancer lineages are Regulation of transcription of nucleolar large rRNA by RNA polymerase I, Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I, and Transcription pausing by RNA polymerase II. Each is linked with ASPSCR1 in more than 13 cancer types. Because this analysis shows association rather than direction, both ASPSCR1-to-partner and partner-to-ASPSCR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of transcription of nucleolar large rRNA by RNA polymerase I grouped by ASPSCR1-low versus ASPSCR1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ASPSCR1→partner) and Y-score (partner→ASPSCR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.210	+0.913	<.001	<.001	3	14
BONE	Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.192	+1.000	<.001	.002	3	14
BONE	Transcription pausing by RNA polymerase II →	+0.233	+1.138	<.001	<.001	2	12
SOFT_TISSUE	Positive regulation of cell morphogenesis →	+0.078	+0.607	<.001	<.001	3	10
OESOPHAGUS	Energy coupled proton transmembrane transport, against electrochemical gradient →	+0.103	+0.951	.001	.001	3	10
OESOPHAGUS	Electron transport coupled proton transport →	+0.103	+0.951	.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,195 associations by consensus.

Regulation of transcription of nucleolar large rRNA by RNA polymerase I by ASPSCR1 expression — BONE

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