ASPM

Across TCGA cell cohorts, ASPM RNA expression is significantly associated with the go_rna of many other GO terms, with 4,600 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ASPM-associated GO terms across cancer lineages are DNA-templated DNA replication maintenance of fidelity, Regulation of chromosome condensation, and Regulation of G2/M transition of mitotic cell cycle. Each is linked with ASPM in more than 19 cancer types. Because this analysis shows association rather than direction, both ASPM-to-partner and partner-to-ASPM results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated DNA replication maintenance of fidelity grouped by ASPM-low versus ASPM-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ASPM→partner) and Y-score (partner→ASPM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	DNA-templated DNA replication maintenance of fidelity →	+0.121	+1.128	<.001	<.001	3	20
SOFT_TISSUE	Regulation of chromosome condensation →	+0.166	+0.916	<.001	<.001	3	20
BREAST	Regulation of G2/M transition of mitotic cell cycle →	+0.072	+1.199	<.001	<.001	3	20
BONE	Mitotic spindle elongation →	+0.299	+1.348	.003	<.001	3	19
OESOPHAGUS	Nuclear division →	+0.113	+1.193	<.001	<.001	3	19
OESOPHAGUS	Microtubule organizing center organization →	+0.119	+1.261	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,600 associations by consensus.

DNA-templated DNA replication maintenance of fidelity by ASPM expression — OESOPHAGUS

Explore this box plot interactively →