ASPHD2

Across TCGA cell cohorts, ASPHD2 mutation is significantly associated with the RNA expression of many other genes, with 23 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ASPHD2-associated genes across cancer lineages are GTSF1L, C6orf118, and CFHR2. Each is linked with ASPHD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ASPHD2-to-partner and partner-to-ASPHD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GTSF1L grouped by ASPHD2-low versus ASPHD2-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ASPHD2→partner) and Y-score (partner→ASPHD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	GTSF1L →	+0.039	+4.544	<.001	.003	3	2
LARGE_INTESTINE	C6orf118 →	+0.102	+3.793	.007	.007	3	1
LARGE_INTESTINE	CFHR2 →	+0.046	+4.437	<.001	.004	3	1
BLOOD_Leukemia	DEFB125 →	+0.035	+4.060	<.001	.003	3	1
BLOOD_Leukemia	RGS7 →	+0.327	+3.769	<.001	.008	3	1
BLOOD_Leukemia	AQP12A →	+0.142	+4.269	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

GTSF1L by ASPHD2 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →