ASPHD1

Across TCGA cell cohorts, ASPHD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,198 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ASPHD1-associated GO terms across cancer lineages are IMP salvage, Notch signaling pathway, and Chromosomal 5-methylcytosine DNA demethylation pathway. Each is linked with ASPHD1 in more than 7 cancer types. Because this analysis shows association rather than direction, both ASPHD1-to-partner and partner-to-ASPHD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IMP salvage grouped by ASPHD1-low versus ASPHD1-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ASPHD1→partner) and Y-score (partner→ASPHD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	IMP salvage →	+0.183	+1.901	.003	.008	3	8
URINARY_TRACT	Notch signaling pathway →	-0.109	-1.845	<.001	<.001	3	7
URINARY_TRACT	Chromosomal 5-methylcytosine DNA demethylation pathway →	-0.107	-1.848	<.001	<.001	3	7
URINARY_TRACT	Regulation of synapse structural plasticity →	+1.176	+2.322	<.001	<.001	3	7
LUNG_NSCLC_LUSC	Regulation of G protein-coupled receptor signaling pathway →	+0.071	+2.158	.001	<.001	3	6
URINARY_TRACT	Cell communication involved in cardiac conduction →	-0.234	-2.771	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,198 associations by consensus.

IMP salvage by ASPHD1 expression — URINARY_TRACT

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