Across TCGA patient cohorts, ASPDH mutation is significantly associated with the total protein of many other genes, with 14 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ASPDH-associated genes across cancer lineages are eIF4G, mTOR_pS2448, and p70-S6K_pT389. Each is linked with ASPDH in more than 1 cancer types. Because this analysis shows association rather than direction, both ASPDH-to-partner and partner-to-ASPDH results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ASPDH→partner) and Y-score (partner→ASPDH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eIF4G →	+0.424	+3.000	.012	.036	3	1
UCEC	mTOR_pS2448 →	-0.238	-2.986	.003	.035	3	1
UCEC	p70-S6K_pT389 →	-0.240	-2.990	.021	.036	3	1
UCEC	p90 RSK_pT359_S363 →	-0.234	-3.169	.035	.020	3	1
UCEC	PDCD4 →	-0.907	-3.169	<.001	.020	3	1
UCEC	S6_pS235_S236 →	-0.502	-3.169	.034	.020	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

Exploration

ASPDH survival (RNA) · tumor vs normal (RNA) · all ASPDH data types