Q-omics provides the consensus-scored ASNSP4 profile across patient tissues and cancer cell-line models. ASNSP4 expression is associated with patient survival in 16 of 34 cancer types, with the highest sampling consensus in LIHC. Among the 18 cancer types available for tumor–normal comparison, ASNSP4 is differentially expressed in 4, with the highest sampling consensus in BRCA. Additionally, ASNSP4 RNA expression shows 5,449 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight LIHC, BRCA, and STAD as cancer lineages where ASNSP4 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for ASNSP4 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes ASNSP4 survival associations across molecular data types. ASNSP4 RNA expression shows survival associations in the most cancer types (16). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible ASNSP4 RNA expression–survival associations across cancer types. High ASNSP4 expression shows unfavorable associations in LIHC, TGCT, UVM, UCEC, ACC and LUAD. The LIHC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify LIHC as the clearest survival context for ASNSP4 RNA expression.
This table summarizes ASNSP4 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 4. The strongest signals are observed in BRCA for RNA.
This table ranks reproducible tumor–normal expression differences for ASNSP4. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. ASNSP4 shows lower tumor expression in ESCA and higher tumor expression in BRCA, KICH and LIHC. The BRCA box plot shows higher ASNSP4 RNA expression in tumor versus normal tissue (log2 FC = +0.023, t-test p = .003).
This table shows molecular features associated with ASNSP4 in patient tissues and cancer cell lines. In patient samples, ASNSP4 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.
