ASNS

Across TCGA patient cohorts, ASNS protein abundance is significantly associated with the RNA expression of many other genes, with 17,306 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ASNS-associated genes across cancer lineages are GARS1, CHAC1, and PSAT1. Each is linked with ASNS in more than 8 cancer types. Because this analysis shows association rather than direction, both ASNS-to-partner and partner-to-ASNS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ASNS versus GARS1 in BRCA, with a Pearson correlation of 0.64.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ASNS→partner) and Y-score (partner→ASNS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	GARS1 →	+0.660	+0.818	<.001	<.001	3	9
HNSC	CHAC1 →	+1.177	+0.540	<.001	<.001	3	9
BRCA	PSAT1 →	+2.265	+0.977	<.001	<.001	3	8
UCEC	HMCN1 →	-1.041	-0.462	<.001	<.001	3	8
BRCA	LDLRAD4 →	-0.829	-0.768	<.001	<.001	3	8
UCEC	SHMT2 →	+0.763	+0.382	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,306 associations by consensus.

ASNS vs GARS1 — BRCA

Explore this scatter interactively →