ASIP

Across TCGA cell cohorts, ASIP RNA expression is significantly associated with the go_rna of many other GO terms, with 2,951 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ASIP-associated GO terms across cancer lineages are Epigenetic regulation of gene expression, Regulation of double-strand break repair, and Regulation of nucleotide-excision repair. Each is linked with ASIP in more than 8 cancer types. Because this analysis shows association rather than direction, both ASIP-to-partner and partner-to-ASIP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Epigenetic regulation of gene expression grouped by ASIP-low versus ASIP-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ASIP→partner) and Y-score (partner→ASIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Epigenetic regulation of gene expression →	+0.054	+1.311	.001	.002	3	9
STOMACH	Regulation of double-strand break repair →	+0.075	+0.396	.003	.006	3	8
STOMACH	Regulation of nucleotide-excision repair →	+0.182	+0.499	<.001	<.001	3	8
BONE	Positive regulation of DNA metabolic process →	+0.065	+1.327	<.001	.001	3	8
STOMACH	Regulation of DNA repair →	+0.064	+0.414	.002	.003	3	8
SOFT_TISSUE	Negative regulation of mRNA processing →	+0.070	+0.146	<.001	.001	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,951 associations by consensus.

Epigenetic regulation of gene expression by ASIP expression — BONE

Explore this box plot interactively →