Across TCGA patient cohorts, ASIC3 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,098 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ASIC3-associated proteins across cancer lineages are HSP90B1, NRBF2, and C1orf116_S519. Each is linked with ASIC3 in more than 4 cancer types. Because this analysis shows association rather than direction, both ASIC3-to-partner and partner-to-ASIC3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ASIC3→partner) and Y-score (partner→ASIC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	HSP90B1 →	-0.324	-0.838	<.001	<.001	3	5
HNSC	NRBF2 →	-0.330	-0.377	<.001	<.001	3	4
OV	C1orf116_S519 →	-0.991	-0.483	.009	.009	3	4
GBM	TMEM102_S246 →	-0.606	-1.143	<.001	.004	3	4
UCEC	TNKS1BP1_S1138 →	-0.608	-0.540	<.001	.004	3	4
BRCA	TPD52L2 →	-0.250	-0.773	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,098 associations by consensus.

Exploration

ASIC3 survival (RNA) · tumor vs normal (RNA) · all ASIC3 data types