Across TCGA patient cohorts, ASIC3 mutation is significantly associated with the RNA expression of many other genes, with 2,822 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ASIC3-associated genes across cancer lineages are ERHP2, ATP1B2, and GDI2P1. Each is linked with ASIC3 in more than 2 cancer types. Because this analysis shows association rather than direction, both ASIC3-to-partner and partner-to-ASIC3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ASIC3→partner) and Y-score (partner→ASIC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	ERHP2 →	+0.102	+4.647	<.001	.007	3	3
UCEC	ATP1B2 →	-0.706	-3.989	.001	<.001	3	3
SKCM	GDI2P1 →	+0.035	+2.155	.001	.002	3	3
BRCA	RNU6-909P →	+0.460	+6.058	.006	<.001	3	2
CESC	RNA5SP394 →	+0.360	+5.345	<.001	.001	3	2
CESC	TRAJ26 →	+0.520	+4.503	.003	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,822 associations by consensus.

Exploration

ASIC3 survival (RNA) · tumor vs normal (RNA) · all ASIC3 data types