ASH2LP2

Across TCGA pan-cancer cohorts, ASH2LP2 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated ASH2LP2 data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher ASH2LP2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ASH2LP2 expression acts as an unfavorable survival marker, although some lineages such as PAAD show a favorable association.

UCS, ACC, and LIHC are the cancer types where ASH2LP2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	OS	Tertile	III,IV	0.170	0.619	.001	72	view →
ACC	DFS	Tertile	IV	0.010	0.383	<.001	45	view →
LIHC	DFS	Tertile	III,IV	0.117	0.369	.010	33	view →
DLBC	OS	Tertile	III,IV	0.175	0.874	.025	27	view →
PAAD	DFS	Tertile	II,III,IV	0.949	0.399	.015	24	view →
READ	DFS	Tertile	IV	0.272	0.657	.010	21	view →
TGCT	DFS	Tertile	III,IV	0.017	0.923	.021	18	view →
LUAD	DFS	Tertile	IV	0.671	0.893	.019	12	view →
STAD	DFS	Tertile	IV	0.278	0.529	.048	9	view →
ESCA	OS	Tertile	III,IV	0.399	0.615	.029	9	view →
SKCM	OS	Tertile	All	0.184	0.397	.037	3	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

ASH2LP2–UCS (OS)

Open the UCS breakdown →