ASH1L

Across TCGA patient cohorts, ASH1L protein abundance is significantly associated with the RNA expression of many other genes, with 10,164 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ASH1L-associated genes across cancer lineages are URB2, ASH1L-AS1, and GPR89A. Each is linked with ASH1L in more than 3 cancer types. Because this analysis shows association rather than direction, both ASH1L-to-partner and partner-to-ASH1L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ASH1L versus URB2 in OV, with a Pearson correlation of 0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ASH1L→partner) and Y-score (partner→ASH1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	URB2 →	+0.562	+0.414	.002	.001	3	3
OV	ASH1L-AS1 →	+0.742	+0.433	.001	.002	3	3
BRCA	GPR89A →	+0.410	+0.377	<.001	<.001	3	3
LUAD	LPGAT1 →	+0.713	+0.716	<.001	.001	3	3
LUAD	PTCD3 →	+0.421	+0.660	<.001	.001	3	3
BRCA	DAP3 →	+0.551	+0.357	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,164 associations by consensus.

ASH1L vs URB2 — OV

Explore this scatter interactively →