ASH1L-AS1

Across TCGA pan-cancer cohorts, ASH1L-AS1 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of ASH1L-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where ASH1L-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types ASH1L-AS1 is over-expressed in tumor, although a few such as KICH and KIRC show the opposite, repressed pattern.

KICH, HNSC, and LIHC are the cancer types where ASH1L-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ASH1L-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Female	II,III,IV	−1.722	<.001	11	view →
HNSC	Male	III,IV	+0.861	<.001	10	view →
LIHC	Female	II,III,IV	+0.818	<.001	9	view →
COAD	Male	II,III,IV	+0.521	<.001	9	view →
KIRC	Male	II,III,IV	−0.636	<.001	7	view →
BLCA	All	III,IV	+0.659	.017	6	view →
THCA	Male	All	−0.465	<.001	6	view →
BRCA	All	All	+0.212	.006	6	view →
CHOL	All	All	+2.082	<.001	5	view →
STAD	All	All	+0.438	.001	5	view →
LUSC	All	All	+0.523	<.001	4	view →
ESCA	All	All	+0.552	.037	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

ASH1L-AS1–KICH

Open the KICH breakdown →