ASGR2

Across TCGA cell cohorts, ASGR2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,898 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ASGR2-associated GO terms across cancer lineages are Alcohol biosynthetic process, Glucocorticoid biosynthetic process, and Ribosomal large subunit assembly. Each is linked with ASGR2 in more than 5 cancer types. Because this analysis shows association rather than direction, both ASGR2-to-partner and partner-to-ASGR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Alcohol biosynthetic process grouped by ASGR2-low versus ASGR2-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ASGR2→partner) and Y-score (partner→ASGR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Alcohol biosynthetic process →	+0.126	+5.389	.001	.004	3	6
LIVER	Glucocorticoid biosynthetic process →	+2.031	+5.235	<.001	.002	3	6
LIVER	Ribosomal large subunit assembly →	+0.114	+5.522	.001	.001	2	6
BLOOD_Leukemia	Negative regulation of cortisol biosynthetic process →	-0.432	-0.896	.008	.004	3	5
BLOOD_Leukemia	Negative regulation of glucocorticoid biosynthetic process →	-0.432	-0.896	.008	.004	3	5
BLOOD_Leukemia	Negative regulation of aldosterone biosynthetic process →	-0.432	-0.896	.008	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,898 associations by consensus.

Alcohol biosynthetic process by ASGR2 expression — LIVER

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