ASF1B

Across TCGA pan-cancer cohorts, ASF1B mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated ASF1B data layer compared with 29 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher ASF1B mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated ASF1B expression acts as an unfavorable survival marker, although some lineages such as LSCC and PDAC show a favorable association.

LSCC, PDAC, and LUAD are the cancer types where ASF1B mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Tertile	II,III,IV	0.957	0.678	.012	21	view →
PDAC	DFS	Median	All	1.000	0.911	.030	4	view →
LUAD	OS	Tertile	III,IV	0.378	0.879	.047	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

ASF1B–LSCC (OS)

Open the LSCC breakdown →