ASF1B

Across TCGA patient cohorts, ASF1B mutation is significantly associated with the RNA expression of many other genes, with 663 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ASF1B-associated genes across cancer lineages are SNORD116-5, MIR4695, and MIR3941. Each is linked with ASF1B in more than 1 cancer types. Because this analysis shows association rather than direction, both ASF1B-to-partner and partner-to-ASF1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORD116-5 grouped by ASF1B-low versus ASF1B-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ASF1B→partner) and Y-score (partner→ASF1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	SNORD116-5 →	+0.291	+4.282	<.001	.009	3	2
LUAD	MIR4695 →	+0.423	+7.930	<.001	.008	3	2
UCEC	MIR3941 →	+0.519	+2.061	.001	.008	3	2
BLCA	MIR182 →	+0.439	+5.251	<.001	.006	3	2
UCEC	COX6B1P3 →	+0.481	+3.090	.001	<.001	3	2
SKCM	OR4X2 →	+0.034	+5.039	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 663 associations by consensus.

SNORD116-5 by ASF1B expression — SKCM

Explore this box plot interactively →