Across TCGA cell cohorts, ASCL4 RNA expression is significantly associated with the go_rna of many other GO terms, with 143 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible ASCL4-associated GO terms across cancer lineages are Regulation of dendrite development, Isopentenyl diphosphate biosynthetic process, mevalonate pathway, and Fc receptor mediated inhibitory signaling pathway. Each is linked with ASCL4 in more than 1 cancer types. Because this analysis shows association rather than direction, both ASCL4-to-partner and partner-to-ASCL4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ASCL4→partner) and Y-score (partner→ASCL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of dendrite development →	+0.062	+0.264	<.001	.006	3	2
BREAST	Isopentenyl diphosphate biosynthetic process, mevalonate pathway →	+0.156	+0.240	<.001	.002	3	2
BREAST	Fc receptor mediated inhibitory signaling pathway →	-1.282	-0.188	<.001	.002	3	2
BLOOD_Myeloma	Nephrogenic mesenchyme development →	+0.235	+0.006	<.001	.004	3	1
BLOOD_Myeloma	Learning →	-0.078	-0.010	<.001	.008	3	1
BLOOD_Myeloma	Response to high light intensity →	+0.142	+0.006	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 143 associations by consensus.

Exploration

ASCL4 survival (RNA) · tumor vs normal (RNA) · all ASCL4 data types