ASCL3

Across TCGA cell cohorts, ASCL3 protein abundance is significantly associated with the RNA expression of many other genes, with 1,629 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ASCL3-associated genes across cancer lineages are FLOT2, FLOT1, and FAM177A1. Each is linked with ASCL3 in more than 3 cancer types. Because this analysis shows association rather than direction, both ASCL3-to-partner and partner-to-ASCL3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ASCL3 versus FLOT2 in BLOOD_Lymphoma, with a Pearson correlation of 0.82.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ASCL3→partner) and Y-score (partner→ASCL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	FLOT2 →	+1.832	+2.552	<.001	<.001	3	4
BLOOD_Lymphoma	FLOT1 →	+2.760	+2.695	<.001	<.001	3	4
BLOOD_Lymphoma	FAM177A1 →	+1.528	+2.086	<.001	<.001	3	4
BLOOD_Lymphoma	MAPK6 →	+1.644	+2.166	.006	.003	3	4
LARGE_INTESTINE	ALG13 →	+0.623	+1.570	.003	.006	3	4
CNS	AP4E1 →	+0.861	+0.984	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,629 associations by consensus.

ASCL3 vs FLOT2 — BLOOD_Lymphoma

Explore this scatter interactively →