Across TCGA cell cohorts, ASCL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,943 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible ASCL2-associated GO terms across cancer lineages are Striated muscle cell proliferation, Positive regulation of excitatory synapse assembly, and White fat cell proliferation. Each is linked with ASCL2 in more than 6 cancer types. Because this analysis shows association rather than direction, both ASCL2-to-partner and partner-to-ASCL2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ASCL2→partner) and Y-score (partner→ASCL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Striated muscle cell proliferation →	+0.077	+0.418	<.001	.002	3	7
BREAST	Positive regulation of excitatory synapse assembly →	+1.237	+1.804	<.001	<.001	3	7
URINARY_TRACT	White fat cell proliferation →	+1.512	+0.757	<.001	<.001	3	6
BREAST	Transport of virus →	-0.215	-1.752	<.001	<.001	2	7
OESOPHAGUS	Regulation of corticotropin secretion →	-1.135	-1.319	.001	.003	3	6
OESOPHAGUS	Positive regulation of corticotropin secretion →	-1.100	-1.255	.001	.004	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,943 associations by consensus.

Exploration

ASCL2 survival (RNA) · tumor vs normal (RNA) · all ASCL2 data types