ASCC2

Across TCGA patient cohorts, ASCC2 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,900 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ASCC2-associated proteins across cancer lineages are CRKL, TBC1D10A, and PITPNB. Each is linked with ASCC2 in more than 5 cancer types. Because this analysis shows association rather than direction, both ASCC2-to-partner and partner-to-ASCC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ASCC2 versus CRKL in LSCC, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ASCC2→partner) and Y-score (partner→ASCC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CRKL →	+0.311	+0.465	<.001	<.001	3	6
OV	TBC1D10A →	+0.405	+0.638	.001	.003	3	5
GBM	PITPNB →	+0.359	+0.351	<.001	<.001	3	5
HNSC	MAPK1 →	+0.200	+0.488	.003	<.001	3	4
HNSC	MTMR3 →	+0.286	+0.435	<.001	.004	3	4
PDAC	MTMR3_S647 →	+0.550	+0.320	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,900 associations by consensus.

ASCC2 vs CRKL — LSCC

Explore this scatter interactively →