ASCC2

Across TCGA cell cohorts, ASCC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,476 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ASCC2-associated GO terms across cancer lineages are Symbiont-mediated disruption of host cellular anatomical structure, Symbiont-mediated disruption of host anatomical structure, and Regulation of Golgi inheritance. Each is linked with ASCC2 in more than 13 cancer types. Because this analysis shows association rather than direction, both ASCC2-to-partner and partner-to-ASCC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Symbiont-mediated disruption of host cellular anatomical structure grouped by ASCC2-low versus ASCC2-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ASCC2→partner) and Y-score (partner→ASCC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Symbiont-mediated disruption of host cellular anatomical structure →	+0.184	+0.882	<.001	<.001	3	14
BREAST	Symbiont-mediated disruption of host anatomical structure →	+0.184	+0.882	<.001	<.001	3	14
URINARY_TRACT	Regulation of Golgi inheritance →	+0.156	+0.842	.002	.001	3	12
SOFT_TISSUE	Cytosolic transport →	+0.062	+0.505	<.001	.007	3	12
LARGE_INTESTINE	Schwann cell differentiation →	+0.090	+0.553	<.001	.001	3	11
LARGE_INTESTINE	Schwann cell development →	+0.105	+0.644	<.001	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,476 associations by consensus.

Symbiont-mediated disruption of host cellular anatomical structure by ASCC2 expression — BREAST

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