ASCC1

Across TCGA pan-cancer cohorts, ASCC1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated ASCC1 data layer compared with 27 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher ASCC1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated ASCC1 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

CCRCC, HNSC, and UCEC are the cancer types where ASCC1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Quartile	All	0.704	0.994	.001	56	view →
HNSC	DFS	Quartile	III,IV	0.710	0.950	.002	16	view →
UCEC	OS	Median	All	1.000	0.902	.006	6	view →
LSCC	DFS	Median	III,IV	0.584	0.948	.019	5	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

ASCC1–CCRCC (OS)

Open the CCRCC breakdown →