ASCC1

Across TCGA cell cohorts, ASCC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,837 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ASCC1-associated GO terms across cancer lineages are Positive regulation of mitochondrial ATP synthesis coupled electron transport, Ornithine metabolic process, and Telomere capping. Each is linked with ASCC1 in more than 8 cancer types. Because this analysis shows association rather than direction, both ASCC1-to-partner and partner-to-ASCC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mitochondrial ATP synthesis coupled electron transport grouped by ASCC1-low versus ASCC1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ASCC1→partner) and Y-score (partner→ASCC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Positive regulation of mitochondrial ATP synthesis coupled electron transport →	+0.161	+1.015	<.001	<.001	3	8
LUNG_SCLC	Ornithine metabolic process →	+0.114	+0.843	.005	.009	3	8
LUNG_NSCLC_LUSC	Telomere capping →	+0.077	+0.621	<.001	.008	3	8
LARGE_INTESTINE	DNA replication, removal of RNA primer →	+0.117	+0.699	.002	.002	2	9
STOMACH	Vesicle tethering to Golgi →	+0.121	+1.304	.002	.001	3	8
LUNG_NSCLC_LUSC	Mitochondrial DNA repair →	+0.172	+1.055	.003	.002	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,837 associations by consensus.

Positive regulation of mitochondrial ATP synthesis coupled electron transport by ASCC1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →