ASB9

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, ASB9 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated ASB9 data layer compared with 24 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher ASB9 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated ASB9 expression acts as an unfavorable survival marker, although some lineages such as PDAC and HNSC show a favorable association.

PDAC, HNSC, and LSCC are the cancer types where ASB9 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
PDACDFSTertileIII,IV0.9710.482.00150view →
HNSCOSQuartileII,III,IV0.8770.590.0085view →
LSCCDFSQuartileAll0.5280.859.0045view →
UCECDFSQuartileII,III,IV1.0000.538.0434view →
GBMDFSMedianAll0.5560.806.0143view →
Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

ASB9–PDAC (DFS)

Kaplan–Meier survival curve for ASB9 mass-spec protein-high vs -low samples in PDAC.

Open the PDAC breakdown →

Exploration