ASB9

Across TCGA patient cohorts, ASB9 mutation is significantly associated with the total protein of many other genes, with 27 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ASB9-associated genes across cancer lineages are Caspase-7-cleavedD198, eEF2, and EGFR_pY1068. Each is linked with ASB9 in more than 1 cancer types. Because this analysis shows association rather than direction, both ASB9-to-partner and partner-to-ASB9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by ASB9-low versus ASB9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ASB9→partner) and Y-score (partner→ASB9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.660	+2.479	.006	.010	3	2
UCEC	eEF2 →	+0.367	+1.807	.012	.027	3	1
UCEC	EGFR_pY1068 →	-0.365	-3.700	<.001	.001	3	1
UCEC	eIF4E →	+0.234	+3.584	.007	.002	3	1
UCEC	A-Raf_pS299 →	-0.162	-1.807	.001	.027	3	1
UCEC	ACC_pS79 →	+0.299	+1.807	.036	.027	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

Caspase-7-cleavedD198 by ASB9 expression — UCEC

Explore this box plot interactively →