ASB8

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ASB8 protein abundance is significantly associated with the RNA expression of many other genes, with 634 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ASB8-associated genes across cancer lineages are CRYAB, CAVIN3, and GPR88. Each is linked with ASB8 in more than 1 cancer types. Because this analysis shows association rather than direction, both ASB8-to-partner and partner-to-ASB8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ASB8 versus CRYAB in UCEC, with a Pearson correlation of 0.75.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ASB8→partner) and Y-score (partner→ASB8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCRYAB →+1.308+0.360.007.00832
UCECCAVIN3 →+2.180+0.580.003.00332
UCECGPR88 →+0.603+0.413.005<.00132
UCECPEG3 →+1.724+0.447<.001.00432
UCECFABP7P1 →+1.437+0.482.002.00132
UCECPHBP13 →+1.900+0.639.002<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 634 associations by consensus.

ASB8 vs CRYAB — UCEC

Per-sample scatter of ASB8 vs CRYAB in UCEC (Pearson r = 0.75).

Explore this scatter interactively →

Exploration