Across TCGA patient cohorts, ASB7 protein abundance is significantly associated with the RNA expression of many other genes, with 2,902 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ASB7-associated genes across cancer lineages are SLC12A6, ZNF124, and WNK4. Each is linked with ASB7 in more than 1 cancer types. Because this analysis shows association rather than direction, both ASB7-to-partner and partner-to-ASB7 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ASB7→partner) and Y-score (partner→ASB7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SLC12A6 →	+1.004	+0.542	<.001	<.001	3	2
BRCA	ZNF124 →	-0.635	-0.454	<.001	<.001	3	2
BRCA	WNK4 →	+1.055	+0.353	.001	<.001	3	2
BRCA	PYY →	+1.050	+0.471	.008	<.001	3	2
BRCA	JRKL →	-1.028	-0.459	<.001	.001	3	2
BRCA	TM2D3 →	+0.336	+0.411	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,902 associations by consensus.

Exploration

ASB7 survival (RNA) · tumor vs normal (RNA) · all ASB7 data types