ASB7

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ASB7 mutation is significantly associated with the RNA expression of many other genes, with 3,378 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ASB7-associated genes across cancer lineages are MIR7150, RNA5SP412, and RNA5SP418. Each is linked with ASB7 in more than 1 cancer types. Because this analysis shows association rather than direction, both ASB7-to-partner and partner-to-ASB7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ASB7→partner) and Y-score (partner→ASB7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADMIR7150 →+0.480+5.392<.001.00232
UCECRNA5SP412 →+0.607+2.119<.001<.00132
UCECRNA5SP418 →+0.771+2.448<.001<.00132
LUSCRNA5SP410 →+0.744+5.309<.001.00332
LUSCRNA5SP417 →+0.806+4.882<.001.00532
LUSCSSX4 →+0.024+4.882.003.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,378 associations by consensus.

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