ASB6

Across TCGA pan-cancer cohorts, ASB6 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated ASB6 data layer compared with 24 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher ASB6 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated ASB6 expression acts as an unfavorable survival marker, although some lineages such as UCEC and LSCC show a favorable association.

UCEC, PDAC, and LSCC are the cancer types where ASB6 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	III,IV	1.000	0.339	.007	16	view →
PDAC	DFS	Quartile	All	0.443	0.861	.035	6	view →
LSCC	DFS	Tertile	II,III,IV	1.000	0.817	.013	3	view →
LUAD	OS	Median	III,IV	1.000	0.763	.036	2	view →
HNSC	DFS	Median	All	0.551	0.722	.049	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

ASB6–UCEC (OS)

Open the UCEC breakdown →