ASB6

Across TCGA patient cohorts, ASB6 mutation is significantly associated with the RNA expression of many other genes, with 2,275 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ASB6-associated genes across cancer lineages are SLC20A1P3, OR4F14P, and TUBB8P5. Each is linked with ASB6 in more than 1 cancer types. Because this analysis shows association rather than direction, both ASB6-to-partner and partner-to-ASB6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC20A1P3 grouped by ASB6-low versus ASB6-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ASB6→partner) and Y-score (partner→ASB6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	SLC20A1P3 →	+0.049	+7.640	<.001	.009	3	2
LUAD	OR4F14P →	+0.041	+6.599	<.001	<.001	3	2
LUAD	TUBB8P5 →	+0.133	+4.345	<.001	.007	3	2
HNSC	RNU4-70P →	+0.643	+7.954	<.001	.008	3	1
HNSC	TTTY2B →	+0.009	+7.954	<.001	.008	3	1
UCEC	BTBD10 →	+0.456	+3.617	.003	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,275 associations by consensus.

SLC20A1P3 by ASB6 expression — BLCA

Explore this box plot interactively →