ASB4

Across TCGA cell cohorts, ASB4 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,437 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ASB4-associated GO terms across cancer lineages are Regulation of synaptic vesicle priming, Oxidative phosphorylation, and Positive regulation of signal transduction by p53 class mediator. Each is linked with ASB4 in more than 5 cancer types. Because this analysis shows association rather than direction, both ASB4-to-partner and partner-to-ASB4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of synaptic vesicle priming grouped by ASB4-low versus ASB4-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ASB4→partner) and Y-score (partner→ASB4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulation of synaptic vesicle priming →	+0.142	+0.878	.001	.002	3	6
UPPER_AERODIGESTIVE_TRACT	Oxidative phosphorylation →	+0.087	+0.124	.001	.009	3	6
OESOPHAGUS	Positive regulation of signal transduction by p53 class mediator →	+0.087	+0.239	<.001	.004	3	6
BLOOD_Myeloma	Glucose catabolic process →	+0.142	+0.034	<.001	.008	3	5
LUNG_SCLC	Regulation of syncytium formation by plasma membrane fusion →	+0.098	+1.203	<.001	<.001	3	5
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.161	+0.148	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,437 associations by consensus.

Regulation of synaptic vesicle priming by ASB4 expression — LUNG_SCLC

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