ASB3

Across TCGA patient cohorts, ASB3 mutation is significantly associated with the RNA expression of many other genes, with 2,064 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ASB3-associated genes across cancer lineages are RNA5SP73, ZNF833P, and RNA5SP358. Each is linked with ASB3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ASB3-to-partner and partner-to-ASB3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP73 grouped by ASB3-low versus ASB3-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ASB3→partner) and Y-score (partner→ASB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNA5SP73 →	+0.456	+5.837	<.001	.001	3	2
CESC	ZNF833P →	+0.077	+4.996	<.001	.002	3	2
LUAD	RNA5SP358 →	+0.500	+4.984	<.001	.005	3	2
LUAD	RNA5SP410 →	+0.347	+5.912	<.001	.001	3	2
COAD	DEFB4B →	+0.671	+5.843	<.001	<.001	3	2
SKCM	CYCSP19 →	+0.202	+4.156	.002	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,064 associations by consensus.

RNA5SP73 by ASB3 expression — CESC

Explore this box plot interactively →