Across TCGA pan-cancer cohorts, ASB2 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated ASB2 data layer compared with 23 for mass-spec protein.
The strongest signal is observed in adrenocortical carcinoma (ACC), where higher ASB2 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ASB2 expression acts as an unfavorable survival marker.
ACC, UCEC, and CHOL are the cancer types where ASB2 Mutation most reproducibly stratifies survival.
Mutation survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.