ASB2

Across TCGA patient cohorts, ASB2 mutation is significantly associated with the RNA expression of many other genes, with 1,421 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ASB2-associated genes across cancer lineages are CRIP1P4, SNORD116-6, and EEF1A1P39. Each is linked with ASB2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ASB2-to-partner and partner-to-ASB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CRIP1P4 grouped by ASB2-low versus ASB2-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ASB2→partner) and Y-score (partner→ASB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	CRIP1P4 →	+0.121	+4.544	.002	.009	3	2
LIHC	SNORD116-6 →	+0.490	+4.308	.001	.007	3	2
LIHC	EEF1A1P39 →	+0.260	+4.690	<.001	.003	3	2
SKCM	MIR6825 →	+0.139	+4.049	<.001	.007	3	2
CESC	RN7SL810P →	+0.166	+4.874	.005	.002	3	2
LIHC	HMGB1P33 →	+0.056	+4.647	.003	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,421 associations by consensus.

CRIP1P4 by ASB2 expression — LIHC

Explore this box plot interactively →