ASB2

Across TCGA cell cohorts, ASB2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,593 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ASB2-associated GO terms across cancer lineages are Skeletal muscle atrophy, Regulation of barbed-end actin filament capping, and Dendritic cell migration. Each is linked with ASB2 in more than 7 cancer types. Because this analysis shows association rather than direction, both ASB2-to-partner and partner-to-ASB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Skeletal muscle atrophy grouped by ASB2-low versus ASB2-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ASB2→partner) and Y-score (partner→ASB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Skeletal muscle atrophy →	-0.559	-0.708	.005	<.001	3	8
SKIN	Regulation of barbed-end actin filament capping →	-0.103	-1.560	<.001	<.001	3	8
LARGE_INTESTINE	Dendritic cell migration →	-0.219	-0.550	<.001	.004	3	8
BLOOD_Leukemia	Positive regulation of cytokine-mediated signaling pathway →	+0.046	+1.084	<.001	<.001	3	7
BREAST	Regulation of response to cytokine stimulus →	+0.044	+0.193	.002	.007	3	7
BLOOD_Leukemia	Positive regulation of response to cytokine stimulus →	+0.044	+1.034	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,593 associations by consensus.

Skeletal muscle atrophy by ASB2 expression — CNS

Explore this box plot interactively →