ASB16

Across TCGA patient cohorts, ASB16 mutation is significantly associated with the RNA expression of many other genes, with 927 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ASB16-associated genes across cancer lineages are ARL6IP1P3, RNU5E-8P, and PPP1R26P4. Each is linked with ASB16 in more than 2 cancer types. Because this analysis shows association rather than direction, both ASB16-to-partner and partner-to-ASB16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ARL6IP1P3 grouped by ASB16-low versus ASB16-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ASB16→partner) and Y-score (partner→ASB16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ARL6IP1P3 →	+0.156	+2.129	.006	.001	3	3
COAD	RNU5E-8P →	+0.322	+4.557	<.001	.004	3	2
COAD	PPP1R26P4 →	+0.006	+6.156	<.001	<.001	3	2
UCEC	SNF8 →	+0.360	+2.534	.004	.001	3	2
UCEC	CTLA4 →	+0.950	+2.545	<.001	.001	3	2
UCEC	MON1A →	+0.440	+3.711	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 927 associations by consensus.

ARL6IP1P3 by ASB16 expression — UCEC

Explore this box plot interactively →