Across TCGA patient cohorts, ASB13 mutation is significantly associated with the RNA expression of many other genes, with 477 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ASB13-associated genes across cancer lineages are RNU4-31P, MIR6500, and TRAJ21. Each is linked with ASB13 in more than 1 cancer types. Because this analysis shows association rather than direction, both ASB13-to-partner and partner-to-ASB13 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ASB13→partner) and Y-score (partner→ASB13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU4-31P →	+0.470	+5.097	<.001	.008	3	2
LUSC	MIR6500 →	+0.573	+5.273	<.001	.006	3	2
UCEC	TRAJ21 →	+0.418	+2.159	<.001	.002	3	2
UCEC	RNA5SP369 →	+0.478	+2.556	<.001	<.001	3	2
UCEC	RNA5SP461 →	+0.154	+3.668	<.001	.009	3	2
BRCA	MIR6821 →	+0.640	+4.243	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 477 associations by consensus.

Exploration

ASB13 survival (RNA) · tumor vs normal (RNA) · all ASB13 data types