Across TCGA patient cohorts, ASB13 mutation is significantly associated with the total protein of many other genes, with 12 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ASB13-associated genes across cancer lineages are ARID1A, A-Raf_pS299, and ERK2. Each is linked with ASB13 in more than 1 cancer types. Because this analysis shows association rather than direction, both ASB13-to-partner and partner-to-ASB13 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ASB13→partner) and Y-score (partner→ASB13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ARID1A →	-0.234	-2.108	.003	.018	3	2
UCEC	A-Raf_pS299 →	-0.147	-1.700	.003	.044	3	1
UCEC	ERK2 →	+0.287	+3.321	<.001	.009	3	1
UCEC	GATA6 →	-0.144	-3.169	.032	.019	3	1
UCEC	MSH2 →	-0.324	-3.295	<.001	.009	3	1
UCEC	N-Cadherin →	+0.229	+2.179	.010	.034	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

Exploration

ASB13 survival (RNA) · tumor vs normal (RNA) · all ASB13 data types