Across TCGA cell cohorts, ASB12 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ASB12-associated genes across cancer lineages are CLEC10A, OR5H14, and TEX43. Each is linked with ASB12 in more than 1 cancer types. Because this analysis shows association rather than direction, both ASB12-to-partner and partner-to-ASB12 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ASB12→partner) and Y-score (partner→ASB12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	CLEC10A →	+0.006	+5.662	.003	.002	3	1
LUNG_NSCLC_LUAD	OR5H14 →	+0.049	+5.228	<.001	.005	3	1
LARGE_INTESTINE	TEX43 →	+0.160	+4.273	<.001	.006	3	1
LARGE_INTESTINE	GPX5 →	+0.259	+4.273	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

ASB12 survival (RNA) · tumor vs normal (RNA) · all ASB12 data types