Across TCGA cell cohorts, ASB12 mutation is significantly associated with the mutation status of many other genes, with 123 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ASB12-associated genes across cancer lineages are OR10C1, TAP2, and C9orf57. Each is linked with ASB12 in more than 1 cancer types. Because this analysis shows association rather than direction, both ASB12-to-partner and partner-to-ASB12 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ASB12→partner) and Y-score (partner→ASB12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR10C1 →	+5.772	+5.772	.002	.002	1	2
LARGE_INTESTINE	TAP2 →	+4.087	+5.044	.001	.001	1	1
LARGE_INTESTINE	C9orf57 →	+5.087	+4.523	.006	.006	1	1
LARGE_INTESTINE	DCTN1 →	+2.865	+4.217	.007	.007	1	1
LARGE_INTESTINE	FBXO47 →	+5.087	+4.523	.006	.006	1	1
LARGE_INTESTINE	PRSS1 →	+3.087	+4.392	.005	.005	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 123 associations by consensus.

Exploration

ASB12 survival (RNA) · tumor vs normal (RNA) · all ASB12 data types