ASB11

Across TCGA cell cohorts, ASB11 RNA expression is significantly associated with the go_rna of many other GO terms, with 822 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ASB11-associated GO terms across cancer lineages are HRI-mediated signaling, Positive regulation of receptor recycling, and Response to axon injury. Each is linked with ASB11 in more than 3 cancer types. Because this analysis shows association rather than direction, both ASB11-to-partner and partner-to-ASB11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HRI-mediated signaling grouped by ASB11-low versus ASB11-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ASB11→partner) and Y-score (partner→ASB11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	HRI-mediated signaling →	+0.101	+0.010	<.001	.006	3	4
SKIN	Positive regulation of receptor recycling →	+0.075	+0.635	<.001	.003	3	4
BREAST	Response to axon injury →	-0.102	-0.006	.003	.007	3	3
SKIN	Regulation of nucleotide catabolic process →	+0.058	+0.651	.003	.002	3	3
SKIN	Negative regulation of TOR signaling →	+0.027	+0.440	<.001	.003	3	3
SKIN	Response to insulin →	+0.041	+0.636	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 822 associations by consensus.

HRI-mediated signaling by ASB11 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →