ASB10

Across TCGA cell cohorts, ASB10 mutation is significantly associated with the RNA expression of many other genes, with 39 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ASB10-associated genes across cancer lineages are OR1L1, LIM2, and TSPAN16. Each is linked with ASB10 in more than 1 cancer types. Because this analysis shows association rather than direction, both ASB10-to-partner and partner-to-ASB10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR1L1 grouped by ASB10-low versus ASB10-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ASB10→partner) and Y-score (partner→ASB10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	OR1L1 →	+0.045	+5.029	<.001	.006	3	2
BREAST	LIM2 →	+0.040	+3.963	<.001	.003	3	1
BREAST	TSPAN16 →	+0.035	+3.758	.009	.007	3	1
BREAST	EMCN →	+0.391	+3.758	<.001	.007	3	1
BREAST	RTL3 →	+0.309	+3.750	.001	.007	3	1
BREAST	OR10K2 →	+0.038	+4.196	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

OR1L1 by ASB10 expression — LUNG_SCLC

Explore this box plot interactively →